Thursdays 5:00pm - 6:00pm (EDT)
EPISODE SUMMARY:
Presenting the positive innovations that Disruption in Healthcare provides!
Healthcare Disruption occurs everyday the typical news shows what is being cutoff, what is being altered, what misinformation exists and other negative attributes. Disruption in healthcare also provides opportunities and new innovations to expedite patient care, diagnosis and treatment. Today's guests are example of how they used disruption and created a positive solution to manage through it while keeping existing protocols in place.
Marc Filerman: https://www.linkedin.com/in/marc-filerman/
David Yang: https://www.linkedin.com/in/drdavidlyang/
#healthcaredisruption
Tune in for this healthy conversation at TalkRadio.nyc
In this episode of Frank About Health, host Frank R. Harrison reunites with fellow Brooklyn Tech alumni David Yang and introduces guest Marc Filerman, a seasoned health tech innovator working at the intersection of medical devices, AI, and entrepreneurship. Together, they explore how disruption in healthcare—rather than being a setback—can be a catalyst for innovation, especially when individuals take an active role in managing their own health and developing solutions. Marc shares insights from his decades-long career in imaging and diagnostics, emphasizing the promise of AI, predictive analytics, and patient empowerment to not only extend life but significantly improve its quality.
In this segment of Frank About Health, host Frank R. Harrison and guests Marc Filerman and David Yang dive deep into the meaning of an “ecosystem” in healthcare innovation—emphasizing that real progress requires collaboration among problem identifiers, problem solvers, and entrepreneurs. Marc argues that while patients are often left out of traditional innovation frameworks, strong patient advocates can drive powerful change and even catalyze entire movements that attract clinical, financial, and technological support. The conversation frames disruption not as chaos but as a constructive reimagining of outdated systems, especially when patients themselves become entrepreneurs solving the very problems they’ve lived with.
In this high-impact segment, Marc Filerman outlines why deeply understanding the patient care pathway—from diagnosis to treatment to monitoring—is critical for effective healthcare innovation, especially in addressing diverse needs across rural and urban populations. He emphasizes that well-defined, specific problem statements (“they have to SUC: Specific, Understandable, Compelling”) are essential not just for product development but also for investor confidence and ecosystem alignment. Through examples like rural stroke care, Filerman and Yang explain how segmentation clarifies the total addressable market and reveals where life-saving innovation can have the most meaningful adoption and clinical impact.
In this closing segment of Frank About Health, Marc Filerman expresses a powerful call to shift healthcare innovation from treatment to prevention, emphasizing the role of AI and data in empowering individuals to make healthier choices before disease sets in. He and David Yang highlight the growing importance of addressing chronic conditions and mental health as society evolves—and discuss how weight-loss medications like GLP-1s signal a paradigm shift in preventive care. Frank closes with gratitude, reflection, and a reminder that disruption, when embraced with discipline and purpose, becomes the catalyst for progress.
00:00:53.080 --> 00:01:04.130 Frank R. Harrison: Hey, everybody! It is June 5, th 2025, and welcome to a brand new episode of Frank about health today. It's kind of a mini reunion, while at the same time a very new and innovative show.
00:01:04.200 --> 00:01:25.569 Frank R. Harrison: It is 2 individuals from the class of 1984 from Brooklyn Technical High school, my Alma mater. And basically, if you remember, David Yang was with me on Frank about health several weeks ago, promoting our well, I guess you could say our homecoming. But the thing was is that it was a tribute to an institution that I have found even more relevant today
00:01:25.730 --> 00:01:48.739 Frank R. Harrison: in my case. 40 years later, when it comes to healthcare and healthcare technology and innovation, something I didn't know back then, but having that stem education definitely did serve me well years later. Now, that being said, you know, we've had Dr. Marshall Runji on 4 separate episodes, promoting his book, The Great Healthcare Disruption.
00:01:48.810 --> 00:01:57.730 Frank R. Harrison: 2 of those episodes. David Yang was also very instrumental in discussing about the book and about how there's disruption in many levels, including
00:01:57.730 --> 00:02:21.279 Frank R. Harrison: the way that our country is going through man-made disruptions of sorts. However, we're not going to spend this episode talking about disruption from a negative angle. We're going to talk about how it provides us to get on our entrepreneurial mindset, especially if we have our own health concerns, that we want to get all the information on and look at disruption as an opportunity for innovation.
00:02:21.300 --> 00:02:38.270 Frank R. Harrison: And that being said, today's special guest, Mark Feilerman, who's from Boston, is working for a very well-known incubator in the area, and a hub that looks at healthcare technologies that would be able to come up with better solutions.
00:02:38.270 --> 00:02:55.079 Frank R. Harrison: better treatment protocols probably even better handheld technology similar to the ones that you, David, have developed at your company. Now, the thing that we are going to do with this particular episode is we will have a discussion, as we normally do, especially in segment. 2.
00:02:55.080 --> 00:03:10.320 Frank R. Harrison: But in segment 3. Mark is, gonna give us a little Mini webinar of sorts to show how you take disruptive issues in healthcare. And if you have the mindset, like I know he does. And like I've been trying to branch out with Marshall Runji.
00:03:10.320 --> 00:03:39.650 Frank R. Harrison: we're going to learn what we do about it, so that, all being said, the only disclaimer I can provide is, this is an opportunity to use Frank about health to learn. These are not the views of talkradio, Dot, Nyc. Or of this show, Frank about health, but it is an open discussion that I look forward to having with both David and Mark. Now, David, I'll let you do the honor of introducing Mark's background and history and everything else, because I know that both of you were in the same class together, and it was thanks to you that we had the chance to meet this week.
00:03:40.350 --> 00:03:54.080 David Yang: Yeah, so I would like to introduce Mark. I've known Mark for many years. Almost as long as I've known my wife. We both started in Brooklyn Technical High School Bay way back in the 1980
00:03:54.260 --> 00:04:14.380 David Yang: over the last year or so I've had time. So I've been viewing just different people's Linkedin profiles. And Mark's profile really caught my attention because of the work that he's doing. He's really, I believe, on the cutting edge of taking great ideas and trying to get them from the brain to the bedside. I think Mark's had a better term for that.
00:04:14.380 --> 00:04:30.089 David Yang: so I reached out with, for to him a couple of weeks ago, and he was same Mark very open, very happy person. And so, Mark, why don't you go ahead and tell us a little bit more about yourself. But I'm so glad and thankful, Mark, that you were able to take time out.
00:04:30.450 --> 00:04:31.252 David Yang: Yeah, for this.
00:04:31.520 --> 00:04:45.609 Marc Filerman: Well, it's it's really my my pleasure. Thanks so much, Dave, for for that introduction. And and, Frank, thank you, very honored to be on the show today. Because it's it's so important to be discussing health.
00:04:46.080 --> 00:05:00.400 Marc Filerman: our own health, our role in our own health, our role in in the adoption of new technologies, etc. So I think we'll have an opportunity to to get into that discussion a little bit more.
00:05:00.740 --> 00:05:01.700 Frank R. Harrison: Absolutely.
00:05:01.850 --> 00:05:12.889 Marc Filerman: To add a little color on on Dave's in introduction. So yes, I'm a proud Brooklyn tech graduate from 1984
00:05:14.080 --> 00:05:15.170 Marc Filerman: hard to
00:05:15.350 --> 00:05:41.470 Marc Filerman: say. But I I've spent after a couple of engineering degrees here in Boston area. Spent 35 years or so in in health tech mostly in large companies, focusing on medical imaging, medical, diagnostic imaging across modalities tmr ultrasound that that and the like.
00:05:41.670 --> 00:06:03.820 Marc Filerman: operating theater devices. So the the bits and pieces that that get applied to the patient, or surround the patient, or enable the patient's innards to be viewed during an operation or surgical note reporting. So I spent a fair amount of time in and around software
00:06:04.060 --> 00:06:11.990 Marc Filerman: and the integration of of software technologies to help electronic health records and help
00:06:13.000 --> 00:06:17.590 Marc Filerman: make information available to the doctor when when they need it.
00:06:18.280 --> 00:06:27.646 David Yang: I'm laughing because, Mark, you're you're you're naming your own poison because I think that there's a a show around the AI part of it. But please keep going.
00:06:27.970 --> 00:06:42.243 Marc Filerman: Yeah. AI, so it's it's funny you bring up AI. So I did graduate work at at Mit in the AI lab back in the late eighties, where I'm fond of saying it was difficult to spell AI
00:06:44.500 --> 00:06:56.549 Marc Filerman: I will say that that whole movement and and many of the people, not myself were really instrumental in in laying the groundwork for for everything that we have today.
00:06:57.520 --> 00:07:25.780 Frank R. Harrison: That being said, I just have one question I mean, I know, for the eighties for me. I was in the Math Science Institute at Brooklyn Tech, and we were learning Pascal programming and basic programming and how to use the Ibm PC. Remember that dinosaur. Meanwhile, the thing is is that AI back then, would not have been what it is today, whether it's Chat Gpt or Alexa devices through your living room, or whatever. What would you classify? Was the AI hot.
00:07:25.780 --> 00:07:38.669 Marc Filerman: Yeah, so the the thing one of the things and my my lens on it. Was really trying to embed smart systems
00:07:38.730 --> 00:08:00.610 Marc Filerman: into products to make those products smarter. So there was this convergence of of software and hardware, so mechanical hardware, electronic hardware to to make like the a classic example, that I remember from 40 years ago was.
00:08:01.290 --> 00:08:13.299 Marc Filerman: you know, Irons, that that if they were upright and on, they didn't turn off, and except after a long, long period of time, but if they were down
00:08:13.730 --> 00:08:17.360 Marc Filerman: with the hot surface down and not moving
00:08:17.520 --> 00:08:21.780 Marc Filerman: for a very short period of time, they would just wait.
00:08:21.780 --> 00:08:23.520 Frank R. Harrison: Turned off right nice.
00:08:23.520 --> 00:08:27.370 Marc Filerman: And and so this there was this convergence of
00:08:27.460 --> 00:08:45.430 Marc Filerman: of software and 3D modeling for product design. So virtual parts and the whole CAD system, computer aid design systems that we're enabling
00:08:46.050 --> 00:09:02.019 Marc Filerman: innovative design and and the the design of more complex products. So so AI was all about expert systems and and smart products, at least in robotics. There were a number of thrusts. But you know, if I could come today.
00:09:02.460 --> 00:09:31.769 David Yang: Yeah, if I could comment. You know, I was in the I am in the medical device industry, and we have instruments that do literally thousands of tests per hour. So if an instrument goes down, then thousands of patients are disrupted, they don't get their results back. So, having anticipating when the machine is going to go down is critical to healthcare, and we're reaching the point where, in 2025, we will now know if David Yang
00:09:31.860 --> 00:09:35.580 David Yang: is about to hit a problem, and he's gonna go down.
00:09:35.580 --> 00:09:36.050 Marc Filerman: Page.
00:09:36.050 --> 00:09:43.400 David Yang: Based on the same idea. But now it's personalized to Frank. Mark, you know. Just yeah.
00:09:43.400 --> 00:09:43.750 Frank R. Harrison: Yes.
00:09:43.750 --> 00:10:08.330 Marc Filerman: So one of the most exciting areas is applying AI to look at extremely large data sets over a long period of time and improve population, health, and then in individuals, health, and to use biomarkers to make predictive comments or predictions about
00:10:08.550 --> 00:10:18.609 Marc Filerman: how an individual should be should behave, what they should do what they shouldn't do, what they should eat, what they shouldn't eat. And there's this.
00:10:19.010 --> 00:10:29.860 Marc Filerman: there's this wonderful convergence now of of patient empowerment and adoption of of innovation that
00:10:30.700 --> 00:10:45.060 Marc Filerman: you know I'm I'm still optimistic that we're going to see people not only living longer, but living better because we've done a fantastic job about making people live longer.
00:10:45.900 --> 00:10:57.840 Marc Filerman: But you know my 95 year old mother, who's bedridden with Alzheimer's and has been for a decade.
00:10:58.310 --> 00:11:05.359 Marc Filerman: No, it she's not living better. She's certainly living longer.
00:11:05.760 --> 00:11:20.859 Frank R. Harrison: Well, the thing is is that at least she's living longer to wait for whatever possible solutions can help mitigate it. But I know it's the age issue. I'm in a situation similar to you. But the difference is, my cousin is 60, 65 going on 66,
00:11:21.580 --> 00:11:26.329 Frank R. Harrison: you know, and so I don't know. Based on the circumstances.
00:11:26.520 --> 00:11:40.709 Frank R. Harrison: I'm not sure how long she's going to be here, and that is an ongoing. I wouldn't call it a trauma. But it's an ongoing problem for me yet what I have learned is to accept that because of AI and other innovations that are out there, there's hope.
00:11:41.040 --> 00:11:41.480 Marc Filerman: Yes.
00:11:41.480 --> 00:11:47.909 Frank R. Harrison: Something that I gather Alzheimer, or pay whether it's family members or patients with Alzheimer's a decade ago
00:11:48.010 --> 00:11:51.059 Frank R. Harrison: probably didn't have much hope. So now there's a little bit more.
00:11:51.900 --> 00:11:58.019 Marc Filerman: It. It's been cool, because after my, my work in in large
00:11:58.410 --> 00:12:10.320 Marc Filerman: Med device and and software companies, these multinational companies, I I got bitten by the entrepreneurial bug at at an orthopedics company.
00:12:10.889 --> 00:12:33.669 Marc Filerman: And and was pretty instrumental by the grace of God, to have been a part of literally building this this business from the from the ground up. And so I. So I quit about 1010 years ago, actually 2,012, 2,013, and I've been entrepreneurial ever since and and squarely on the
00:12:33.690 --> 00:12:41.999 Marc Filerman: on the side of of innovation and and have learned viscerally through the 2 startups that I've I've founded.
00:12:42.340 --> 00:12:42.740 Frank R. Harrison: Yes.
00:12:42.740 --> 00:12:53.679 Marc Filerman: The challenges of innovation, adoption, and the importance of of some, some themes that we will talk about later later during the hour but
00:12:54.100 --> 00:12:54.750 Frank R. Harrison: Awesome.
00:12:54.750 --> 00:12:56.770 Marc Filerman: And it's a lovely journey. So.
00:12:56.770 --> 00:13:26.163 Frank R. Harrison: Well, at the same time, like what David and I have been talking about, especially on our shows involving Marshall Runji is that we're learning that with the way AI has developed over time, and not to mention that when you are dealing with disruption you almost have to be entrepreneurial, to keep focus on your life while you know the rest of society is all fragmented with information or misinformation, and things like that. So is it safe to say before we go to our 1st break, that health tech, or even
00:13:26.740 --> 00:13:33.730 Frank R. Harrison: health disruption is an entrepreneurial mission that we all have to eventually face.
00:13:34.830 --> 00:13:35.809 Marc Filerman: I would need.
00:13:35.810 --> 00:13:40.770 Frank R. Harrison: Learned that in school. So I guess I'm just trying to figure out. Is that what you've discovered through your own experience?
00:13:40.770 --> 00:13:43.690 Marc Filerman: Absolutely and
00:13:44.990 --> 00:14:08.789 Marc Filerman: in innovation, translation, which we'll talk about a little bit, is inherently an entrepreneurial in endeavor. You kind of have to be a little wacky, or at least irrationally persistent. In your belief that somehow you
00:14:09.110 --> 00:14:12.150 Marc Filerman: person individual can
00:14:12.670 --> 00:14:23.420 Marc Filerman: create capital. I impact and and help patients. Which is not always easy. But yes, I would totally concur.
00:14:23.420 --> 00:14:35.050 Frank R. Harrison: I know I'm on the right path. All right, ladies and gentlemen, please stay tuned right here on Frank, about health, as we are managing healthcare disruption through innovation with David Yang and Mark Feilerman. We will be back
00:14:35.220 --> 00:14:36.230 Frank R. Harrison: in a few.
00:16:18.470 --> 00:16:36.790 Frank R. Harrison: Hey, everybody! And welcome back for all of you watching right now, either on Youtube, Linkedin, Facebook or Twitch. If you have any questions during the next half hour, especially as Mark will show us a presentation later on. Please feel free to write in the chat boxes, and we are here to answer those questions, for you live
00:16:36.790 --> 00:16:52.540 Frank R. Harrison: at the same time. What you've just had is an overview that health care when we are dealing with disruption, or if we're dealing with chronic illness, you have to take the bull by the horns and control your ship, your ship to solutions your ship
00:16:52.540 --> 00:17:06.910 Frank R. Harrison: to finding out different inventions that may or may not exist that you could come up with. We all went through Covid. That was a big incubator of sorts, so that being said, I would dub Segment 2, as
00:17:06.970 --> 00:17:33.869 Frank R. Harrison: I already put it down here, and I can't remember it. Development of the ecosystem, because that is essentially what we all have to do for ourselves, for our loved ones, and I guess, as a society, we have to do it more than ever. So that being, said Mark. Let's start with you. Or maybe, David, do you want to define ecosystem? Because I know we were the ones that brainstormed that that was the whole discussion point that we wanted to bring out on this show.
00:17:34.590 --> 00:17:42.030 David Yang: Yeah, I mean, the ecosystem is basically the the collection of all the stakeholders required to take
00:17:42.240 --> 00:17:52.309 David Yang: an idea in disrupting health care to the bedside. And so we've. I've seen many great ideas
00:17:52.450 --> 00:17:56.929 David Yang: that have died on the vine, because that's all. It was was a great idea.
00:17:57.589 --> 00:18:02.199 David Yang: Basically, you need to have a medical need, a clinical need.
00:18:02.340 --> 00:18:02.780 Frank R. Harrison: Right.
00:18:02.940 --> 00:18:11.490 David Yang: And you have to have the clinicians buy in. If this is a test, you have to get the buy-in of the laboratories that are going to do the test.
00:18:11.620 --> 00:18:19.670 David Yang: The the Cfos who are responsible for making sure that everyone, you know, earns a living around that
00:18:20.167 --> 00:18:25.310 David Yang: and so so it's not just the idea, but it's really all the stakeholders.
00:18:25.815 --> 00:18:31.930 David Yang: I'm gonna let Mark speak. I'm also gonna close my window because there's some construction going on. So yeah, go ahead. Mark, yeah.
00:18:31.930 --> 00:18:32.550 Frank R. Harrison: Okay.
00:18:32.550 --> 00:18:51.559 Marc Filerman: Yeah. So so, Dave, thanks for that. I I completely agree that when I, when I, when you define ecosystem sort of in the context of health tech, healthcare, disruption. It is really that that constellation of all of the different
00:18:51.560 --> 00:19:04.870 Marc Filerman: players or actors that have an interest in some sort of innovation or play a role in the adoption of that innovation.
00:19:05.140 --> 00:19:12.679 Marc Filerman: What is very interesting to me is the fact that usually in ecosystem maps.
00:19:12.680 --> 00:19:13.120 David Yang: Bye.
00:19:13.863 --> 00:19:20.762 Marc Filerman: The patient is not explicitly listed, and that's
00:19:21.760 --> 00:19:32.710 Marc Filerman: with with good, you know. Good reason and sort of bad reason. The the good, the good or the the good reason or the explanation is that typically the patient?
00:19:32.820 --> 00:19:54.229 Marc Filerman: It is not the one involved in developing or adopting or buying or using a piece of medical equipment like a big MRI system. Right? The patient kind of walks in after the doctor refers the patient to go to an MRI. But they're not
00:19:54.370 --> 00:20:02.639 Marc Filerman: so. They're they're involved. But but they're not involved in this sort of adoption of that innovation.
00:20:02.790 --> 00:20:07.780 Marc Filerman: So as as we as we think about innovation.
00:20:08.080 --> 00:20:21.060 Marc Filerman: There are multiple, very important people. And I'll just use you know, Boston, New York.
00:20:21.460 --> 00:20:34.735 Marc Filerman: Minneapolis, Chicago, Northern California, and Southern California. Actually Houston, there there are notable places of of hardcore development, Tennessee, also with Vanderbilt.
00:20:36.120 --> 00:20:46.429 Marc Filerman: where there is this critical mass of problem identifiers.
00:20:46.590 --> 00:20:53.509 Marc Filerman: the clinicians that live and deal with problems of patients or workflow or systems every day.
00:20:54.760 --> 00:21:01.940 Marc Filerman: Problem solvers. So engineers, scientists, doctors, researchers that
00:21:02.070 --> 00:21:13.020 Marc Filerman: can develop solutions to these problems that the clinicians or or hospital administrators identify and entrepreneurs.
00:21:14.160 --> 00:21:14.780 Frank R. Harrison: Yes.
00:21:15.120 --> 00:21:20.589 Marc Filerman: And many times, and I have direct experience with this.
00:21:21.696 --> 00:21:32.820 Marc Filerman: We, as innovators and disruptors, believe wrongly that it is enough to have
00:21:33.580 --> 00:21:38.949 Marc Filerman: and problem identifier and a problem solver and money.
00:21:41.030 --> 00:22:00.400 Marc Filerman: And that is not the way that innovation translates. As Dave was saying, from brain to bedside, I love that. I was thinking, a different be from bench to bedside. But there's lots of bees that are all applicable. And I actually like your framework better.
00:22:00.620 --> 00:22:01.489 Marc Filerman: Oh, okay.
00:22:01.490 --> 00:22:05.596 David Yang: I was trying to remember what your 1st B was, so.
00:22:06.190 --> 00:22:15.649 Marc Filerman: But but it's really like innovation is is your B right? Innovation is the stuff that's in the brain that we that somebody
00:22:16.030 --> 00:22:17.120 Marc Filerman: thinks about.
00:22:17.260 --> 00:22:23.970 Marc Filerman: But innovation is not impact.
00:22:24.260 --> 00:22:28.329 Marc Filerman: Innovation requires translation.
00:22:29.220 --> 00:22:34.920 Marc Filerman: So the commercialization of innovation is
00:22:36.660 --> 00:22:43.129 Marc Filerman: is, is translation right? So having the innovation publishing a paper
00:22:44.190 --> 00:22:52.740 Marc Filerman: pumping out Phds great. But to make patient capital, I impact, it has to be out in the world.
00:22:52.960 --> 00:22:58.050 Marc Filerman: and that's where the entrepreneur comes in. That person takes
00:22:58.180 --> 00:23:10.880 Marc Filerman: takes the problem. I you know, it can can readily identify. That's a that's a good problem. And wow, you have a fantastic solution. And I'm gonna come in. And I am going to drive this
00:23:11.310 --> 00:23:33.980 Marc Filerman: this program, this venture forward. And I'm gonna go out and I'm gonna use my grit. And I'm gonna use my muscle. And I'm gonna use my contacts. And I'm gonna not get any sleep. And I'm gonna get funding from wherever I can to to try to take this innovation and translate it into the world.
00:23:34.000 --> 00:23:43.989 Marc Filerman: So the core elements are problem identifiers, problem solvers, entrepreneurs. And typically these surround academia. And then you sprinkle on some.
00:23:44.220 --> 00:23:50.190 Marc Filerman: some some money government incentives, and then you have an ecosystem.
00:23:50.890 --> 00:24:16.189 Frank R. Harrison: Well, you know, it's kind of interesting, because what about? Never mind, Covid, that was an anomaly unto itself. But when you have someone like myself, who's been living my life with epilepsy. 1st seizure at Brooklyn, Tech, March 1984. Your year. The point of the matter is is that I had no idea why I was given that until I realized it became one of the defining marks of my career. Post the music industry. Now, that being said.
00:24:16.280 --> 00:24:38.359 Frank R. Harrison: I now use epilepsy, as I guess you could say, a badge of honor, or as my leverage in order for me to talk about healthcare. This podcast was born on that alone. So my question to you, based on everything you've just said is that even though the patient is not normally looked at as part of the participants in the ecosystem. If they have a unique illness.
00:24:38.470 --> 00:24:45.389 Frank R. Harrison: or if they're bringing to the table something that is unexplainable, isn't that their differential advantage. Isn't that.
00:24:45.390 --> 00:24:45.850 Marc Filerman: Yes.
00:24:45.850 --> 00:24:47.510 Frank R. Harrison: Become the prototype of sorts.
00:24:47.690 --> 00:24:57.459 Marc Filerman: So I I love so thank you for for raising that, because the the advocate, the champion
00:24:57.620 --> 00:25:04.819 Marc Filerman: of a a patient advocate, a patient champion can move mountains.
00:25:05.520 --> 00:25:10.129 Frank R. Harrison: I can literally move mountains because of that person's.
00:25:10.600 --> 00:25:18.500 Marc Filerman: Raising awareness of a specific illness, a specific condition that
00:25:19.070 --> 00:25:22.309 Marc Filerman: that they, because of their actions.
00:25:22.450 --> 00:25:27.720 Marc Filerman: bring to the attention of the ecosystem and coalesce.
00:25:28.200 --> 00:25:45.830 Marc Filerman: The problem solvers the money, the the structure, the the the frameworks, the non-dilutive funding initiatives from a state or a city or a local government. So a patient, a strong, patient advocate
00:25:46.090 --> 00:25:53.510 Marc Filerman: can coalesce other patients and literally create a movement to raise visibility of a condition
00:25:53.620 --> 00:25:57.489 Marc Filerman: which catches the eye of the innovators. And like, Wow, that's a.
00:25:57.940 --> 00:26:04.980 Marc Filerman: and I'm trying not to being from New York. It's so hard not to cur, particularly when I get excited about things. But it's so.
00:26:04.980 --> 00:26:05.760 Frank R. Harrison: Okay.
00:26:05.760 --> 00:26:11.210 Marc Filerman: Important to to to have that. So there's this wonderful
00:26:12.090 --> 00:26:16.479 Marc Filerman: 2 sides of the coin. You know, you've got. The the patients
00:26:16.800 --> 00:26:30.229 Marc Filerman: on one side is sort of the innovation ecosystem, and that's actually a bad analogy. I would say that the motivation for the ecosystem, the motivation for everything in the aforementioned ecosystem is actually the patient
00:26:30.430 --> 00:26:36.349 Marc Filerman: right? Whether they're specifically involved in that translation or or not.
00:26:37.120 --> 00:26:37.550 Frank R. Harrison: Yes.
00:26:37.550 --> 00:26:52.220 Marc Filerman: They are the core right, solving, helping Frank live the life that Frank wants to live, and giving Frank the tools to do that in the way that Frank wants to do that.
00:26:52.370 --> 00:26:55.039 Marc Filerman: Yeah, it's an incredibly important motivator.
00:26:55.040 --> 00:27:08.939 Frank R. Harrison: I guess the movement becomes even more compelling if the patient is, the advocate is the entrepreneur, and therefore brings everything to the table. But of course they can't do it alone. No entrepreneur can do anything alone. They need the right team.
00:27:09.170 --> 00:27:22.300 Marc Filerman: So did in fact, there are many, many instances of entrepreneurs with a certain condition that say, you know what I've been suffering.
00:27:23.260 --> 00:27:25.490 Marc Filerman: and no solutions are out there.
00:27:26.800 --> 00:27:30.349 Marc Filerman: I'm gonna do it myself, and I'll stay cool.
00:27:30.780 --> 00:27:31.210 Marc Filerman: 2
00:27:31.710 --> 00:27:48.510 Marc Filerman: to be an entrepreneur, and maybe having no knowledge of entrepreneurship, not being a problem solver necessarily by training, but because of grit and motivation they are.
00:27:49.000 --> 00:27:57.679 Marc Filerman: They create a company to solve that problem. I I've I've worked with countless companies where that's
00:27:57.800 --> 00:28:01.880 Marc Filerman: that. That has been the case, and they make fantastic engineers.
00:28:01.880 --> 00:28:13.289 Frank R. Harrison: That is amazing. That is amazing. So then would it be also safe to say that part of the disruption that Marshall has talked about in his book, and that David and I were assessing throughout the last month or so.
00:28:13.410 --> 00:28:15.979 Frank R. Harrison: Is that what is disrupted
00:28:16.190 --> 00:28:32.520 Frank R. Harrison: is the homeostatic state is the norm when we are in the chaos, and that entrepreneur takes over, as you said, that actually is not disruption. It's it's the norm for them. But it is a positive form of disruption. Right? Would that be the best way to differentiate.
00:28:32.690 --> 00:28:39.420 Marc Filerman: Yeah. I I would say so. That that state of
00:28:39.750 --> 00:28:49.210 Marc Filerman: in inherent discontent is a is a hallmark of of entrepreneurs. Yes.
00:28:49.210 --> 00:28:50.529 Marc Filerman: When do you say that?
00:28:50.910 --> 00:29:02.200 David Yang: No, that that's right. And you know, I was just thinking of another story where I actually went to a core lab, a core testing lab in a hospital.
00:29:02.520 --> 00:29:03.690 David Yang: And one of the
00:29:03.890 --> 00:29:19.600 David Yang: standard work in that core hospital lab is that they have to centrifuge blood for reasons that I don't want to get into. But there's a step where you have to centrifuge blood. The nurse practitioner. Whoever has to go there and sit in front of this machine for 5 min before it can go on to the instrument.
00:29:19.760 --> 00:29:25.000 David Yang: and I told her, well, what if I told you you didn't have to do that, and she got very angry.
00:29:25.080 --> 00:29:50.009 David Yang: She said, look, David, I've been doing this job for 30 years. You have to do this. Everyone always has to do this. And what I pointed out is that what you need is the product, that step that you having to do it? There could be a better way. And I explained to her a better way. Then her whole demeanor changed. Which is, you mean? I don't have to do this 5 min step anymore. I it can just go from the body to the instrument.
00:29:50.120 --> 00:29:54.990 David Yang: and I don't have to babysit it, Yada. Then her entire demeanor changed because
00:29:55.310 --> 00:30:01.170 David Yang: she was accepting of the current states. And you know, and when you think about
00:30:01.300 --> 00:30:06.010 David Yang: the current state is just that. But the future state doesn't have to look like the current state.
00:30:06.220 --> 00:30:20.520 Marc Filerman: And so so I love that example. Right? So one of the things that entrepreneurs realize inherently is that
00:30:20.840 --> 00:30:32.820 Marc Filerman: everything around us is a construct that was made by somebody, and I can unmake it.
00:30:33.270 --> 00:30:35.330 David Yang: Yeah, they can improve it.
00:30:35.490 --> 00:30:44.080 Marc Filerman: I can do that. I can self actualize. Yeah. And I can present to this.
00:30:44.180 --> 00:30:48.229 Marc Filerman: to the, to the norm, to the status quo a
00:30:48.430 --> 00:30:56.129 Marc Filerman: different way of doing something which may may, which may meet with massive resistance
00:30:56.525 --> 00:31:22.230 Marc Filerman: initially, but as soon as they say, Oh, wait a minute. You were. You are making my life easier or better, or you're improving patient care, or you're you're you're keeping the same efficacy, but reducing the side effects, or you're shortening the the recovery time, or you're increasing the the meantime between seizures, or you're reducing the amplitude of the whatever it is like.
00:31:23.340 --> 00:31:25.089 Marc Filerman: Okay, now, I'm really interested.
00:31:25.690 --> 00:31:26.910 David Yang: Right, appreciate it.
00:31:26.910 --> 00:31:28.815 Marc Filerman: Please. Keep talking.
00:31:29.820 --> 00:31:38.189 Frank R. Harrison: Take our second break right now. I did want to say, however, that what you've just shown is that the health care disruptor that most people should
00:31:39.311 --> 00:31:43.799 Frank R. Harrison: get pulled towards is the visionary entrepreneur.
00:31:44.080 --> 00:31:55.990 Frank R. Harrison: All right, that all being said, we're now going to in segment. 3. Have a little bit of a Webinar slash lecture from Mark Feilerman. But I did want to say that we will be focused on
00:31:56.600 --> 00:32:00.870 Frank R. Harrison: the path to patient-centered care. Correct. That's the title that we gave it.
00:32:02.360 --> 00:32:03.640 Frank R. Harrison: Or okay, that.
00:32:03.640 --> 00:32:04.060 David Yang: I'll figure.
00:32:04.060 --> 00:32:08.224 Frank R. Harrison: Said, I'm like literally looking at.
00:32:08.680 --> 00:32:09.090 Marc Filerman: Yes.
00:32:09.090 --> 00:32:09.880 Frank R. Harrison: Yeah, I.
00:32:09.880 --> 00:32:11.869 Marc Filerman: Patch to pass the patient.
00:32:12.010 --> 00:32:13.700 Frank R. Harrison: The patient care pathway.
00:32:14.580 --> 00:32:18.448 Frank R. Harrison: Okay, alright, everybody. Stay tuned. We'll be back in a few.
00:33:49.460 --> 00:33:52.430 Frank R. Harrison: Hey, everybody, and welcome back the patient.
00:33:53.850 --> 00:34:02.330 Frank R. Harrison: Oh, wow! Why can't I get it right? You! Why don't you say it, Mark? Because I know I love your. I love your energy when it comes to this topic, so
00:34:02.880 --> 00:34:05.260 Frank R. Harrison: just say it like it's so like it's spelled it out.
00:34:05.480 --> 00:34:07.860 Marc Filerman: Patient care, pathways.
00:34:07.860 --> 00:34:08.350 Frank R. Harrison: Yes.
00:34:08.350 --> 00:34:20.059 Marc Filerman: The patient journey, and why? Yes, and why this is is so important to understand.
00:34:21.080 --> 00:34:24.279 Marc Filerman: In in in translation. So
00:34:25.139 --> 00:34:28.650 Marc Filerman: so I think I will be able to
00:34:28.719 --> 00:34:49.319 Marc Filerman: to show some slides here. But but before I do so, we're talking about disruption. We're talking about the adoption of innovation, the translation of of innovation and the difficulties that entrepreneurs can encounter
00:34:49.320 --> 00:35:04.100 Marc Filerman: when they are trying to get their their innovation adopted. And there's so many different ways to fail, but notably one of the most important things
00:35:04.320 --> 00:35:10.665 Marc Filerman: to to understand. And it's directly related to the
00:35:12.330 --> 00:35:24.900 Marc Filerman: the the patient care pathway, and to the adoption of innovation is that it is absolutely, positively critical
00:35:26.090 --> 00:35:32.389 Marc Filerman: for startups to have well-defined problem statements. And actually, Frank, you know, it's funny.
00:35:32.870 --> 00:35:36.010 Marc Filerman: This can sometimes be a problem
00:35:36.420 --> 00:35:55.919 Marc Filerman: for patient entrepreneurs because they live. These problems ubiquitously, and the problems with certain conditions affect multiple areas of of a patient's life that it can be difficult
00:35:56.640 --> 00:36:03.209 Marc Filerman: to really understand. Well, what am I? What problem I am I actually trying to solve?
00:36:03.510 --> 00:36:09.069 Marc Filerman: And the the problems that clinicians face
00:36:09.400 --> 00:36:13.550 Marc Filerman: are different than the life of the patient.
00:36:13.760 --> 00:36:31.829 Marc Filerman: and this is where that split between the patient being involved in the ecosystem and the and the translation of innovation. And the and the doctor really manifests because the doctor, or the hospital, or the administrator, or the or the chief, or the the surgeon advocate, is
00:36:32.440 --> 00:36:52.839 Marc Filerman: is the person that's going to pay for for a solution to a problem. And if you, as an entrepreneur, don't frame that problem correctly, they're not going to understand it. They may feel like, I don't own that problem. I'm sort of tangentially related to it. But I don't own that problem.
00:36:53.382 --> 00:37:07.000 Marc Filerman: And and the patient's like, wait a minute. Hold on, you entrepreneur, and you, clinician, you know you you guys talk to one another because I'm I'm suffering and and all of that's true. But the way that that
00:37:07.740 --> 00:37:20.400 Marc Filerman: that miscommunication can be clarified is to have very well defined problem states. And this having a well defined problem statement is absolutely, positively critical
00:37:21.630 --> 00:37:38.180 Marc Filerman: because it frames the whole company and allows the the customer, the partner, the investor, to really understand what is motivating that entrepreneur. What is motivating that founding team and allows me
00:37:38.370 --> 00:37:45.020 Marc Filerman: as a Funder, as a as an angel investor, to accept
00:37:45.290 --> 00:37:49.440 Marc Filerman: the value that you're bringing through that innovation.
00:37:49.620 --> 00:37:56.069 Marc Filerman: Because, like, oh, I understand the problem. And I agree that it's actually a big problem.
00:37:56.430 --> 00:38:08.360 Marc Filerman: It's not just a problem that Frank has that Mark has. This is actually a problem that many patients have. And this is where the power of that
00:38:08.550 --> 00:38:35.129 Marc Filerman: that patient advocate can be can be critical, because that patient advocate can coalesce everybody, drive the innovation and having a well-defined problem statement can tie right back to the value that in innovation is is delivering. But there's depth, and there's nuance and heterogeneity ubiquitously in our healthcare system.
00:38:35.250 --> 00:38:40.070 Marc Filerman: which is which is a real problem and a real
00:38:40.240 --> 00:38:50.429 Marc Filerman: hurdle for adoption. And, Dave, I know you've you've seen this on the on the corporate side. I've seen it on the corporate and and on the
00:38:50.610 --> 00:39:00.970 Marc Filerman: and on this the startup side and and having this real depth and understanding of the problem is is critical.
00:39:01.350 --> 00:39:01.710 Frank R. Harrison: Right.
00:39:01.710 --> 00:39:13.290 David Yang: Yeah, okay. You know, I can't emphasize that more. A stroke patient, a potential stroke patient. If you're in an urban area, has a very different
00:39:13.660 --> 00:39:23.229 David Yang: patient care pathway than a rural. If you get a stroke in Boston, New York, la! You probably will go to a stroke center right away.
00:39:23.660 --> 00:39:30.110 David Yang: If you're in a rural setting and you're a suspected stroke, you may go to the community hospital.
00:39:30.310 --> 00:39:33.759 David Yang: They may figure out that you have the stroke, but they can't do anything about it.
00:39:33.980 --> 00:39:47.159 David Yang: So then they're going to put you back in an ambulance and send you on another journey to the stroke center, which could be an hour, an hour and a half away. So the nuance, the depth, the geographical.
00:39:47.580 --> 00:39:48.080 Marc Filerman: Yes.
00:39:48.080 --> 00:39:59.019 David Yang: Characteristics of health care. You know something in rural Georgia that I spent some time studying is very different than you know. Downtown, you know. Boston, yeah.
00:39:59.020 --> 00:39:59.480 Frank R. Harrison: Hmm.
00:39:59.480 --> 00:40:13.189 Marc Filerman: And so these so having a a clear understanding of that patient journey, and what we mean by that, and what what Dave was was referring to in the in the stroke situation is
00:40:13.390 --> 00:40:20.579 Marc Filerman: is what happens to that patient from essentially the time of symptoms to
00:40:21.010 --> 00:40:26.069 Marc Filerman: treatment, to monitoring. And maybe even so, there's sort of 3 3
00:40:26.700 --> 00:40:35.339 Marc Filerman: phases right? That diagnosis which is usually coincident with symptoms treatment and then monitoring. And to be able to
00:40:35.860 --> 00:40:42.890 Marc Filerman: to really understand how a specific type of patient with a specific
00:40:43.180 --> 00:40:50.690 Marc Filerman: instance of a disease or condition is going to be diagnosed, treated, and monitored.
00:40:50.830 --> 00:40:53.100 Frank R. Harrison: Can really affect.
00:40:54.230 --> 00:41:00.100 Marc Filerman: Where that entrepreneur and where that startup wants to focus their attention.
00:41:00.350 --> 00:41:07.250 Marc Filerman: because there's a a huge need in in healthcare deserts.
00:41:07.730 --> 00:41:08.160 Frank R. Harrison: Yes.
00:41:08.160 --> 00:41:14.889 Marc Filerman: You know, which are many times correlated with with ruralness. Not always.
00:41:16.430 --> 00:41:19.159 Marc Filerman: Ver, you know, for for stroke patients
00:41:19.746 --> 00:41:27.039 Marc Filerman: versus in Boston, and it's perfectly acceptable to say, look, I have designed this thing
00:41:27.860 --> 00:41:37.710 Marc Filerman: as a as a solution, right? Or I am looking to commercialize this thing through my startup and my target customer.
00:41:37.980 --> 00:41:45.330 Marc Filerman: my intended user buyer, are the people in these types of ecosystems.
00:41:45.550 --> 00:41:46.680 Frank R. Harrison: So.
00:41:47.910 --> 00:41:51.939 Marc Filerman: The the number of stroke patients.
00:41:52.050 --> 00:41:59.509 Marc Filerman: or the number of strokes that happens in the United States every year, is an interesting
00:41:59.930 --> 00:42:12.100 Marc Filerman: number, but not necessarily the problem statement. And that may or may not actually guide what you're doing. What a segue. So these contextual statements.
00:42:12.210 --> 00:42:22.530 Marc Filerman: right about rates of cancer or rates. And cancer is a great one, because it's not. It's not that it's great, but it's a great example for what we're talking.
00:42:24.900 --> 00:42:37.809 Marc Filerman: these contexts. These are not problem statements. And we we many times confuse the fact that you know a certain cancer rate or a certain number of strokes that happen
00:42:38.190 --> 00:42:48.899 Marc Filerman: equals. Hey, we have this huge value proposition when, in fact, the way innovation happens is that yeah, we're gonna we're gonna further refine.
00:42:49.530 --> 00:43:09.589 Marc Filerman: Our understanding of the problem based upon our understanding of the patient journey in rural Georgia, and that patient's care pathway, and use that to guide the development of the product, to solve that specific problem by providing this specific
00:43:09.890 --> 00:43:11.350 Marc Filerman: value proposition.
00:43:11.880 --> 00:43:30.730 Marc Filerman: And these things are critical. So I love to say euphemistically, that problem statements have to suck your problem statement as an engineer has to suck, it has to be specific, understandable, and compelling. SUC. Has to suck
00:43:32.240 --> 00:43:33.750 Marc Filerman: excellent.
00:43:33.840 --> 00:43:34.490 Marc Filerman: So.
00:43:34.490 --> 00:43:45.610 Frank R. Harrison: Do have a I have an interesting question, though, that I don't know if it's a marketing oriented question. But when you were talking about the rural cases of stroke victims
00:43:46.010 --> 00:43:53.079 Frank R. Harrison: where they have more delay in treatment because of their journey and the location, and whether the resources are available or not.
00:43:53.300 --> 00:44:00.000 Frank R. Harrison: Does it then, therefore, tell the entrepreneur that they have to segment their solution to the problem.
00:44:00.000 --> 00:44:00.690 Marc Filerman: Absolutely.
00:44:00.850 --> 00:44:01.860 David Yang: So.
00:44:01.860 --> 00:44:02.610 Frank R. Harrison: Having more.
00:44:02.610 --> 00:44:03.190 David Yang: Absolutely.
00:44:03.620 --> 00:44:04.779 Marc Filerman: Absolutely, so.
00:44:04.780 --> 00:44:05.860 Frank R. Harrison: Okay.
00:44:06.010 --> 00:44:14.670 Marc Filerman: So so part of specific. The S in suck is like specific, and that specific is based upon a segmentation.
00:44:15.078 --> 00:44:21.429 Marc Filerman: And so I I do a little angel investing in the Boston area right? And so talk to a lot of entrepreneurs.
00:44:21.530 --> 00:44:30.020 Marc Filerman: and when it becomes very clear that they have not
00:44:30.280 --> 00:44:38.080 Marc Filerman: segmented or don't understand the segmentation of their users and their buyers and their their ecosystem.
00:44:38.590 --> 00:44:43.589 Marc Filerman: That's like an automatic out, because one of the things that I'm looking for
00:44:43.730 --> 00:44:54.910 Marc Filerman: is deep, deep expertise in the understanding of the problem, understanding of the patient journey and the nuances, understanding of the different care pathways and where they're kit
00:44:55.140 --> 00:45:02.500 Marc Filerman: can best be applied in a foothold market, and how that foothold market can be broadened.
00:45:02.500 --> 00:45:03.000 Frank R. Harrison: Awesome.
00:45:03.580 --> 00:45:09.139 David Yang: So if I just could just quickly add, so imagine that you had a stroke test
00:45:09.340 --> 00:45:17.650 David Yang: right? So there are a million strokes in the Us. Back in 2019, as I recall, that's the total market.
00:45:17.950 --> 00:45:20.870 David Yang: But you may want to focus on the rural.
00:45:21.010 --> 00:45:31.230 David Yang: because that's because the people in the city. They're going to go to the stroke center, no matter what. So you don't need a stroke test for that. But maybe you need a stroke test that goes in an ambulance.
00:45:31.470 --> 00:45:54.519 David Yang: and if you do the math, maybe 400,000 strokes or potential strokes in the Us. Or in the rural setting. So the total market is about a million. But the total addressable market for your product is 400,000. So now you have a better idea as to really how much financial return you could make, how many customers that you could address, because you've segmented it.
00:45:54.520 --> 00:45:55.070 Marc Filerman: Good night.
00:45:55.520 --> 00:45:58.150 David Yang: You know, according to whatever the right characteristics.
00:45:58.150 --> 00:46:02.120 Marc Filerman: Exactly. And what's so cool about this is that
00:46:02.380 --> 00:46:06.510 Marc Filerman: it may be that there are only 400,000,
00:46:06.910 --> 00:46:27.410 Marc Filerman: not the 1 million, but the magnitude of the amplitude of the problem is so much greater for these, this segment of patients that, like, okay, you know, the the adoption hurdles are significantly less, and people will use that test every day.
00:46:27.750 --> 00:46:29.950 Marc Filerman: Yep, so
00:46:30.350 --> 00:46:42.979 Frank R. Harrison: We're about to take our final break. But I was just gonna make. I hope this is appropriate the joke that came to my mind. It sounds like that. Certain entrepreneurs in that particular instance. They don't suck, they get stuck.
00:46:44.310 --> 00:46:49.099 Marc Filerman: I love it, I'll I'll use that and credit you next time.
00:46:50.140 --> 00:46:50.530 Frank R. Harrison: Dirt.
00:46:50.530 --> 00:46:52.430 David Yang: I'm gonna use it. But I'm not crediting you.
00:46:53.523 --> 00:46:55.409 Frank R. Harrison: That's okay.
00:46:55.410 --> 00:47:03.930 Frank R. Harrison: All right. So. But I'm crediting both of you for being on this episode of Frank about health, and that being said, we will be back in a few.
00:48:47.350 --> 00:49:01.330 Frank R. Harrison: Hey, everybody, and welcome back. Well, overall, I think, Mark, like what I was saying. We had done our own little draft of what we were going to talk about today, but I think our organic way of talking about it was exactly what was deserved, because.
00:49:01.330 --> 00:49:24.279 Frank R. Harrison: if anything, I felt like I learned a lot more than I knew an hour ago. So I appreciate that. And then, David, thank you again for bringing Mark from our old days at tech to frank about health, because I now know that, like what the title of this segment is about, the future is in our hands. And I wanted basically to spend the remaining.
00:49:24.280 --> 00:49:46.100 Frank R. Harrison: I think it's 5 min of the show to pretty much take what we've discussed today, knowing that healthcare disruption is a constant, not a variable, but that the entrepreneurial mind needs to look at it as opportunity and not a threat, even though the media likes to make everything threatening just for show and tell. But that being said, if we at least
00:49:46.280 --> 00:50:13.450 Frank R. Harrison: own our future, whether it's with a condition or without, if we want to be an advocate or engage in preventative care. Or if we want to create an incubator of our own, whether in my case, it's a healthcare podcast and all health, related Media. Or if it is in David's case, a new medical technology like the way your company worked on Crispr, you know, I think the thing that I would like to find out from you, Mark, before we go.
00:50:13.450 --> 00:50:29.810 Frank R. Harrison: is, can you tell me what you have done in your career in terms of healthcare innovations. I know it's health tech. But were they mainly centered around illnesses? Or were they centered around technology devices, or even something other than we've spoken about today?
00:50:30.340 --> 00:50:58.079 Marc Filerman: Yeah. So so I've I've co-founded 2 2 ventures. Myself. One was a a nuclear imaging company. That's that's now back back in the lab and the other was a a home tech Co. Company to try to keep the elderly safe at home for longer. So so both were around pretty specific problems. But I but I will say that that my
00:50:59.360 --> 00:51:10.720 Marc Filerman: my long term aspiration, personally and and for all of us is to is to shift away from treatment
00:51:11.400 --> 00:51:14.000 Marc Filerman: and move towards prevention
00:51:14.610 --> 00:51:27.659 Marc Filerman: to the extent that we can. Certain. You know, diseases and conditions are hereditary, or they are really beyond our control, through through trauma, or what? What have you?
00:51:28.270 --> 00:51:35.090 Marc Filerman: But there are many chronic diseases that can be
00:51:35.280 --> 00:51:43.919 Marc Filerman: significantly reduced, if not eliminated, maybe not eliminated, but reduced right by
00:51:44.490 --> 00:51:52.240 Marc Filerman: by changing how we changing what we as individuals do, and and my sort of big
00:51:52.670 --> 00:51:56.700 Marc Filerman: frustration being part of the
00:51:56.810 --> 00:52:03.250 Marc Filerman: innovation and translation ecosystem is that we? We are not
00:52:03.520 --> 00:52:16.400 Marc Filerman: focused enough on on prevention, and and too much on on therapy. And I'm really looking to AI to be able to help
00:52:16.540 --> 00:52:28.963 Marc Filerman: inform patients at a population level and at an individual level, so that we are power empowered as people to to make better choices. Yes.
00:52:30.930 --> 00:52:34.940 Marc Filerman: yeah. So I I would say that that.
00:52:35.370 --> 00:52:44.840 Marc Filerman: Oh, yeah, that that we, my personal, you know, involvement and has always been problem problem problem solved.
00:52:44.840 --> 00:52:56.145 David Yang: And and you know, touching on that Marshall Runge's book on the great Healthcare Disruption talks about the latest miracle drug that really might be a miracle drug, which is these
00:52:56.670 --> 00:53:01.019 David Yang: glp drugs to help reduce weight.
00:53:01.797 --> 00:53:18.519 David Yang: Because of all the comorbidities associated with, you know, obesity, you know, high blood pressure, heart disease, you know, diabetes, etc. Etc. Etc. So focusing on preventive, you know, healthy lifestyle means that you don't.
00:53:19.060 --> 00:53:31.999 David Yang: We need the therapies. Obviously, because this isn't going to help everyone, but it minimizes the need for therapies as you get older. You know these chronic illnesses that could be prevented by by simple things.
00:53:33.090 --> 00:53:41.350 Frank R. Harrison: That being said, would you say that if we got to that point where we mainly are all focused on preventative? The way that both you and David just outlined
00:53:41.380 --> 00:54:06.470 Frank R. Harrison: with things like the glp-one drugs. Would we then, therefore, be a society or a medical ecosystem, where the main ongoing treatments are in the areas of mental and neurological health, because those are things that are not containable, especially when it's not a tangible illness. Epilepsy is about electricity. It's not about a tumor, you know. So I mean. But that's just my own personal.
00:54:06.470 --> 00:54:08.560 Frank R. Harrison: Yeah. So no, what you know better.
00:54:08.560 --> 00:54:32.000 Marc Filerman: So. So I am. The the brain is like like the ocean sort of just a mystery, right? And and the biology in the body is just so insanely complicated, particularly looking at it from a little mechanical engineer's perspective. Not a scientist. I don't even play one on TV. You know that that I really.
00:54:32.910 --> 00:54:39.310 Marc Filerman: at the risk of jumping on the AI bandwagon? You know I'm I'm really hoping that
00:54:39.540 --> 00:54:43.520 Marc Filerman: that large data sites can help us
00:54:44.240 --> 00:54:48.231 Marc Filerman: with some transformational and profound
00:54:49.160 --> 00:54:56.570 Marc Filerman: insights that will allow us to understand mechanisms of action.
00:54:57.406 --> 00:55:09.020 Marc Filerman: Particularly around things that are not like a physical tumor, but they are electrical pathways they and and enable, and that these models will enable us
00:55:09.230 --> 00:55:11.080 Marc Filerman: to associate
00:55:11.290 --> 00:55:25.359 Marc Filerman: in ways that we can't now like. Oh, the electrical pathway is actually affected by this particular protein. Under these circumstances, or what have you right where we're not really able to understand the
00:55:25.590 --> 00:55:28.239 Marc Filerman: the mechanism of action entirely.
00:55:28.540 --> 00:55:29.100 Frank R. Harrison: Hmm.
00:55:29.940 --> 00:55:30.950 Marc Filerman: But
00:55:32.740 --> 00:55:43.149 Marc Filerman: mental health, loneliness, depression, anxiety. These things are on the rise. I'm also hoping that we can.
00:55:43.590 --> 00:55:50.740 Marc Filerman: as a society, learn to utilize this thing and and social
00:55:51.740 --> 00:55:53.140 David Yang: Frank about health.
00:55:53.140 --> 00:55:54.260 David Yang: Better to learn.
00:55:54.260 --> 00:55:55.030 Frank R. Harrison: Thank you. I appreciate it.
00:55:55.476 --> 00:55:56.814 David Yang: About health. Yes.
00:55:57.260 --> 00:56:19.220 Frank R. Harrison: Absolutely well, I mean, if anything, not just frank about health, but our alliance at Brooklyn Tech, even though I'm class of 85, and you both are 84, you and I, David, have an alliance on the stem committee that we're still involved with, and I figure it has shown me. You know we all graduate from college or graduate school or med school law school. What a business school, whatever it is.
00:56:19.220 --> 00:56:28.740 Frank R. Harrison: and we all think that that is our career, Alma Mater, I would have to say, I agree. And in the case of health care innovation that we've been discussing about.
00:56:28.760 --> 00:56:34.339 Frank R. Harrison: I really think that for the 3 of us it began at Brooklyn Tech. I really believe that.
00:56:34.340 --> 00:56:39.179 Marc Filerman: Oh, absolutely love! Love for chemistry happened right right there.
00:56:39.180 --> 00:56:39.690 Frank R. Harrison: Yes.
00:56:39.690 --> 00:56:43.779 Marc Filerman: Organic, inorganic qual and quant. That's right.
00:56:44.730 --> 00:56:56.269 Frank R. Harrison: Remember Ap physics ap bio calculus pro computer programming. I mean, I actually think that is what triggered my epileptic seizure. So maybe that was the opportunity.
00:56:56.640 --> 00:56:57.010 Frank R. Harrison: No.
00:56:57.560 --> 00:57:11.649 David Yang: You know, kind of, although what these subjects are all important, I think it's having the discipline to sit through it and to grind through it. You know a lot of people think that these are well, you know, you just have to be smart and you can do it. But
00:57:11.810 --> 00:57:23.739 David Yang: you know you have to be enthusiastic, but you also have to have be patient, and you have to grind through a lot of this stuff. I mean, you know physics. I like physics, but it wasn't
00:57:23.890 --> 00:57:27.680 David Yang: something that I woke up. And I was like, Wow, I want to do this. But.
00:57:27.680 --> 00:57:28.080 Frank R. Harrison: Yes.
00:57:28.080 --> 00:57:45.120 David Yang: But the the grinding, the the discipline to go through that. I think you know many of the high achievers, many of the entrepreneurs that's part of their personality that they will be as enthusiastic about the messy boring stuff as they are with the cool stuff.
00:57:45.850 --> 00:58:11.339 Frank R. Harrison: It became part of our toolkit. Yeah, all right, ladies and gentlemen, I am sorry we are signing off in about less than a minute. I want to thank Mark Feilerman and David Yang for being on this very important episode of Frank about health. You have seen over the last 5, 6 weeks that I have been on a campaign for going through the disruption that we are seeing in our society as well as in
00:58:11.340 --> 00:58:23.890 Frank R. Harrison: technology. And I'm trying to use this as the positive direction that we have to all go forward with. So that being said, as Mark suggested, stay tuned next week to a new episode of Frank about health.
00:58:23.890 --> 00:58:51.260 Frank R. Harrison: But, or even as David, you were saying, it was a very informative tool for all of us to really continue following up on. I also want to point out at 6 o'clock. Success with a splash is going to be coming on, and I just want all of you out there to please ask me or David, or mark any questions, because when this show gets replayed on Youtube, you can reach out to all of us. I'm Frank Rharrison, one@gmail.com mark. Where can they reach you?
00:58:51.540 --> 00:58:56.929 Marc Filerman: Yes. Mc fileerman@gmail.com.
00:58:57.140 --> 00:58:58.120 Frank R. Harrison: And David.
00:58:58.910 --> 00:59:02.549 David Yang: David L. yang@icloud.com.
00:59:02.550 --> 00:59:11.809 Frank R. Harrison: Okay, so, ladies and gentlemen, we are signing off right now. Stay tuned for success with a splash. Thank you to Jesse behind the scenes, and thank you again for being here. See you next week.
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